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Nat Neurosci. 2009 Jan;12(1):32-4. doi: 10.1038/nn.2228. Epub 2008 Nov 23.

Connectivity-based segregation of the human striatum predicts personality characteristics.

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1
Department of Epileptology and Life & Brain Center, Department of NeuroCognition, University of Bonn, Sigmund Freud Street 25, Bonn 53105, Germany. mikexcohen@gmail.com

Abstract

We found that personality characteristics are linked to dissociable connectivity streams in the human brain. Whereas fiber tracts between a subcortical network, including the hippocampus and amygdala, and the ventral striatum predicted individual differences in novelty seeking, tracts between prefrontal cortex and the striatum predicted individual differences in reward dependence. These findings suggest that the strength of limbic-striatal connectivity may, in part, underlie human personality traits.

PMID:
19029888
DOI:
10.1038/nn.2228
[Indexed for MEDLINE]
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