Format

Send to

Choose Destination
Endocrinol Metab Clin North Am. 2008 Dec;37(4):857-71. doi: 10.1016/j.ecl.2008.08.006.

The microbes of the intestine: an introduction to their metabolic and signaling capabilities.

Author information

1
Institute for Genome Sciences, University of Maryland, School of Medicine, 20 Penn Street, Baltimore, MD 21201, USA.

Abstract

This article summarizes advances in the field of host-microbe interactions in the gut. The human gut is home to a complex community of microbes (the microbiota) that plays a critical role in host nutrient acquisition and metabolism, development of intestinal epithelial cells, and host immune system. Genetic background, nutritional status, and environmental factors influence the structure and function of the gut microbiota. Networks for cell-cell communication include microbes actively communicating with microbes of the same and other species; host cells recognizing and interacting with commensal versus pathogenic organisms; and microbes releasing peptides that resemble peptide hormones of vertebrates, possibly influencing host cell function.

PMID:
19026936
PMCID:
PMC4411945
DOI:
10.1016/j.ecl.2008.08.006
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Elsevier Science Icon for PubMed Central
Loading ...
Support Center