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Bull Exp Biol Med. 2008 Jan;145(1):47-50.

Metabolic effects of Trekrezan during adaptation of rats to intermittent hypoxic hypoxia.

Author information

1
Department of Pharmacology, Military Medical Academy, Russian Ministry of Defense, St. Petersburg.

Abstract

The animals were adapted to intermittent hypoxic hypoxia in a flow pressure chamber for 3 days. Each one-day training session consisted of 4 elevations to an altitude of 6000 m for 20 min (15 m/sec, 20-min intervals between assents). Trekrezan (25 mg/kg intraperitoneally) was injected immediately after the end of daily training over 3 days. We showed that trekrezan increased the degree of adaptive metabolic changes in the brain, heart, and liver of rats during adaptation to hypoxic hypoxia.

PMID:
19024000
DOI:
10.1007/s10517-008-0010-0
[Indexed for MEDLINE]

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