Format

Send to

Choose Destination
J Cardiovasc Electrophysiol. 2009 Apr;20(4):416-21. doi: 10.1111/j.1540-8167.2008.01352.x. Epub 2008 Nov 11.

Predicting recurrence of vasovagal syncope: a simple risk score for the clinical routine.

Author information

1
Department of Cardiology, University Heart Center, Hamburg, Germany. aydin@uke.de

Abstract

BACKGROUND:

Predictors for recurrence of syncope are lacking in patients with vasovagal syncope. The aim of this study was to identify risk factors for recurrence of syncope and develop a simple prognostic risk score of clinical value.

METHODS:

Two hundred seventy-six patients with a history of vasovagal syncope were prospectively followed for 2 years. Diagnosis of vasovagal syncope was based on clinical history and negative standard work-up. Inclusion in the study was independent from the result of the head-up tilt test, which was performed in all cases. Risk factors for syncope recurrence were evaluated by the Cox proportional hazards regression model and implemented in a risk score, which was validated with the log-rank test and an internal cross-validation.

RESULTS:

The Cox-regression analysis identified the number of previous syncopal events, history of bronchial asthma, and female gender as predictors for syncope recurrence (all P < 0.05). In contrast, head-up tilt test response had no predictive value (P = 0.881). Developing a risk score, study patients were identified as having high (recurrence rate during 2 years of follow-up: 37.2%), intermediate (24.8%), and low (6.5%) risk for syncope recurrence (receiver operating characteristic [ROC] of score 0.83, P < 0.01; Log-rank test for event-free survival, P < 0.005).

CONCLUSIONS:

In patients with vasovagal syncope, risk of recurrence can be stratified and is predictable based on a simple risk score.

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center