Format

Send to

Choose Destination
Vaccine. 2009 Jan 14;27(3):416-20. doi: 10.1016/j.vaccine.2008.10.074. Epub 2008 Nov 17.

Risk factors for nosocomial rotavirus infection in a paediatric hospital: the potential role for rotavirus vaccine use.

Author information

1
Infection Control Service of the Professor Hosannah de Oliveira Paediatric Centre, Federal University of Bahia, Salvador, Brazil.

Abstract

To analyze the incidence and risk factors (RF) of nosocomial infection (NI) in a paediatric teaching hospital, a retrospective cohort study was conducted in Salvador, Brazil. The Centres for Disease Control and Prevention definitions were used. The detection of the rotavirus antigen in stool was performed using a rapid latex agglutination test. The study group comprised 2978 admissions that accounted for 32,924 patient-days. The incidence of NI was 8.3/1000 patient-days and 9.2/100 admissions. Of the 274 NI episodes, the most common illness and causative agent were gastroenteritis (125; 45.6%) and rotavirus (59; 21.5%), respectively. The RF for rotavirus NI was young age (10+/-8 months vs. 27+/-33 months; mean difference 17 months, 95% CI 15-20 months, p < 0.001). The temporal distribution of community-acquired and NI rotavirus showed similar trends. The universal use of rotavirus vaccine is a potential tool to control NI among children.

PMID:
19014989
DOI:
10.1016/j.vaccine.2008.10.074
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center