Crosstalk among Histone Modifications

Cell. 2008 Nov 14;135(4):604-7. doi: 10.1016/j.cell.2008.10.036.

Abstract

Histone modifications play a complex role in the regulation of transcription. Recent studies (Duncan et al., 2008; Lee et al., 2007; Li et al., 2008) reveal that regulation of histone modifications can be functionally linked to reinforce the activation or repression of gene expression.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review
  • Comment

MeSH terms

  • Animals
  • Chromosomes / metabolism
  • DNA-Directed RNA Polymerases / metabolism
  • Drosophila
  • Gene Expression
  • Histones / chemistry
  • Histones / metabolism*
  • Humans
  • Mice
  • Models, Biological
  • Protein Processing, Post-Translational
  • Saccharomyces cerevisiae / metabolism
  • Schizosaccharomyces / metabolism
  • Transcription, Genetic

Substances

  • Histones
  • DNA-Directed RNA Polymerases