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Semin Perinatol. 2008 Dec;32(6):413-8. doi: 10.1053/j.semperi.2008.09.010.

Nonthyroidal illness syndrome and euthyroid sick syndrome in intensive care patients.

Author information

1
The Regional Neonatal Center-Maria Fareri Children's Hospital at Westchester Medical Center/New York Medical College, Valhalla, New York 10595, USA. sergio_golombek@nymc.edu

Abstract

This article reviews the pathophysiology of non-thyroidal illness syndrome (NTIS) and euthyroid sick syndrome (ESS), a multifactorial phenomenon characterized by suppression of thyroid hormone levels that has been described in several disease states, probably due to different causes in different patients. It also describes the laboratory values of thyroid function tests (TFTs), relevant animal studies, the association of NTIS and ESS with cardiovascular problems and sepsis, and the rationale for treatment.

PMID:
19007679
DOI:
10.1053/j.semperi.2008.09.010
[Indexed for MEDLINE]

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