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Org Biomol Chem. 2008 Dec 7;6(23):4293-5. doi: 10.1039/b815064h. Epub 2008 Oct 17.

Stereoselective synthesis of the hormonally active (25S)-delta7-dafachronic acid, (25S)-Delta4-dafachronic acid, (25S)-dafachronic acid, and (25S)-cholestenoic acid.

Author information

1
Department Chemie, Technische Universität Dresden, Bergstrasse 66, 01069 Dresden, Germany.

Abstract

We report a stereoselective synthesis of the (25S)-cholestenoic-26-acids which are highly efficient ligands for the hormonal receptor DAF-12 in Caenorhabditis elegans.

PMID:
19005586
DOI:
10.1039/b815064h
[Indexed for MEDLINE]

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