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J Neurosci. 2008 Nov 12;28(46):11753-9. doi: 10.1523/JNEUROSCI.3797-08.2008.

Epigenetics in the nervous system.

Author information

1
Brudnick Neuropsychiatric Research Institute, University of Massachusetts Medical School, Worcester, Massachusetts 01604, USA.

Abstract

It is becoming increasingly clear that epigenetic modifications are critical factors in the regulation of gene expression. With regard to the nervous system, epigenetic alterations play a role in a diverse set of processes and have been implicated in a variety of disorders. Gaining a more complete understanding of the essential components and underlying mechanisms involved in epigenetic regulation could lead to novel treatments for a number of neurological and psychiatric conditions.

PMID:
19005036
PMCID:
PMC3844836
DOI:
10.1523/JNEUROSCI.3797-08.2008
[Indexed for MEDLINE]
Free PMC Article

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