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J Asian Nat Prod Res. 2008 Sep-Oct;10(9-10):933-7. doi: 10.1080/10286020802240301.

Microbial transformation of alantolactone by Mucor polymorphosporus.

Author information

1
The State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China.

Abstract

Two new transformed sesquiterpenes of alantolactone by Mucor polymorphosporus were obtained. They were characterized as 3beta-hydroxy-11betaH-eudesm-5-en-8beta,12-olide (2) and 3beta,11alpha-dihydroxy-eudesm-5-en-8beta,12-olide (3), on the basis of spectral methods including 2D NMR. And product 3 was an unusual hydroxylation derivative of alantolactone at C-11.

PMID:
19003611
DOI:
10.1080/10286020802240301
[Indexed for MEDLINE]

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