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FEBS Lett. 1991 Feb 11;279(1):110-4.

The oxygenation of cholesterol esters by the reticulocyte lipoxygenase.

Author information

1
Institute of Biochemistry, School of Medicine (Charité), Humboldt University, Berlin, Germany.

Abstract

The arachidonate 15-lipoxygenase from rabbit reticulocytes oxygenates cholesterol esters containing polyenoic fatty acids. Cholesterol esterified with saturated fatty acids is not oxygenated. The structures of the oxygenation products formed from various cholesterol esters have been identified by high pressure liquid chromatography, UV-spectroscopy and gas chromatography/mass spectroscopy. Oxygenated cholesterol esters have been detected in atherosclerotic plaques of human aortas.

PMID:
1899834
[Indexed for MEDLINE]
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