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Nucleic Acids Res. 2009 Jan;37(Database issue):D852-7. doi: 10.1093/nar/gkn732. Epub 2008 Nov 7.

INTERFEROME: the database of interferon regulated genes.

Author information

1
Center for Innate Immunity and Infectious Diseases, Monash Institute of Medical Research, Monash University, Clayton, Victoria, Australia.

Abstract

INTERFEROME is an open access database of types I, II and III Interferon regulated genes (http://www.interferome.org) collected from analysing expression data sets of cells treated with IFNs. This database of interferon regulated genes integrates information from high-throughput experiments with annotation, ontology, orthologue sequences from 37 species, tissue expression patterns and gene regulatory information to enable a detailed investigation of the molecular mechanisms underlying IFN biology. INTERFEROME fulfils a need in infection, immunity, development and cancer research by providing computational tools to assist in identifying interferon signatures in gene lists generated by high-throughput expression technologies, and their potential molecular and biological consequences.

PMID:
18996892
PMCID:
PMC2686605
DOI:
10.1093/nar/gkn732
[Indexed for MEDLINE]
Free PMC Article

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