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Neuron. 2008 Nov 6;60(3):477-82. doi: 10.1016/j.neuron.2008.10.020.

Strength through diversity.

Author information

1
Department of Biology and National Center for Behavioral Genomics, Brandeis University, MS 008, 415 South Street, Waltham, Massachusetts 02454-9110, USA.

Abstract

The remarkable versatility of the mammalian brain is made possible by a huge diversity of cellular plasticity mechanisms. These include long-term potentiation and depression at both excitatory and inhibitory synapses, as well as a variety of intrinsic and homeostatic plasticity mechanisms. A fundamental challenge for the field is to assemble our detailed knowledge of these specific mechanisms into a coherent picture of how plasticity within cortical circuits works to tune network properties.

PMID:
18995822
PMCID:
PMC4919814
DOI:
10.1016/j.neuron.2008.10.020
[Indexed for MEDLINE]
Free PMC Article

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