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Nephrol Dial Transplant. 2009 Apr;24(4):1220-6. doi: 10.1093/ndt/gfn609. Epub 2008 Nov 5.

Comparison of the prevalence of chronic kidney disease among different ethnicities: Beijing CKD survey and American NHANES.

Author information

1
Institute of Nephrology Peking University First Hospital, 8 XiShiKu Street, XiCheng District, Beijing 100034, China.

Abstract

BACKGROUND:

It is unclear whether ethnic disparity of the prevalence of chronic kidney disease (CKD) exists among native Chinese and American ethnicities.

METHODS:

A stratified multistage clustered screening for CKD performed in Beijing in 2006 was compared with data from the National Health and Nutrition Examination Survey (NHANES) between 1999-2006 (participants aged > or =20 years, 13 626 Chinese, 9006 whites, 3447 African Americans, 4626 Hispanics). Serum creatinine from Beijing and NHANES were calibrated at the Cleveland Clinic Laboratory. The re-expressed abbreviated MDRD equation for Americans and its modified form for Chinese were used to estimate glomerular filtration rate (eGFR). Subjects with eGFR <60 mL/min/1.73 m(2) were diagnosed as having chronic renal insufficiency (CRI). Albuminuria was diagnosed if the urine albumin-creatinine ratio was >17 mg/g for males or >25 mg/g for females. CKD was diagnosed if CRI or albuminuria was present.

RESULTS:

Compared with American whites, African Americans and Hispanics, Chinese had a lower prevalence of adjusted albuminuria (12.10%, 16.33% and 14.16% versus 9.27%), CRI (9.46%, 5.18% and 3.11% versus 1.38%) and CKD (19.03%, 19.00% and 15.99% versus 10.25%). Moreover, Chinese hold the lowest risk of albuminuria when exposed to diabetes; the risk of CRI among Chinese when exposed to diabetes or hypertension was lower than that among African Americans, but similar to that among whites and Hispanics.

CONCLUSIONS:

The CKD prevalence was significantly different among native Chinese and American ethnicities.

PMID:
18987261
DOI:
10.1093/ndt/gfn609
[Indexed for MEDLINE]

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