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Pediatr Blood Cancer. 2009 Mar;52(3):420-2. doi: 10.1002/pbc.21788.

Severe vitamin B-12 deficiency in a child mimicking thrombotic thrombocytopenic purpura.

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1
Department of Hematology Oncology, Children's Hospital Oakland, Oakland, California 94609, USA. adimond@gmail.com

Abstract

We report a case of severe vitamin B-12 deficiency in a child who had a clinical presentation of hemolysis and thrombocytopenia that suggested the diagnosis of thrombotic thrombocytopenic purpura (TTP) and was associated with decreased ADAMTS13 activity. In this report, we review vitamin B-12 deficiency in children, the relationship between ADAMTS13 activity and TTP and discuss other conditions associated with decreased ADAMTS13 activity.

PMID:
18985742
DOI:
10.1002/pbc.21788
[Indexed for MEDLINE]
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