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J Am Chem Soc. 2008 Nov 26;130(47):15756-7. doi: 10.1021/ja8051415.

A unifying nitrososynthase involved in nitrosugar biosynthesis.

Author information

1
Department of Chemistry, Vanderbilt University, Nashville, Tennessee 37235, USA.

Abstract

Herein we describe the cloning, functional expression and initial characterization of ORF36 from Micromonospora carbonacae var. africana and rubN8 from Streptomyces achromogenes var. rubradiris. The purified enzymes play the same role, the double-oxidation of TDP-evernosamine to TDP-evernitrosose in the everninomycin and rubradirin pathways, respectively.

PMID:
18983146
PMCID:
PMC2661260
DOI:
10.1021/ja8051415
[Indexed for MEDLINE]
Free PMC Article

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