Format

Send to

Choose Destination
Genes Dev. 2008 Nov 1;22(21):2908-13. doi: 10.1101/gad.1740808.

New cell or new cycle?

Author information

1
Institute of Human Genetics, CNRS, Montpellier, France.

Abstract

In mammals, trophoblast giant (TG) cell differentiation is characterized by a physiological endoreduplication, resulting in genome size augmentation. A recent study by Ullah and colleagues (pp. 3024-3036), published in this issue of Genes & Development, now elucidates the role of the cyclin-dependent kinase inhibitors (CKIs), p21 and p57, in mammalian endocycle regulation.

PMID:
18981469
DOI:
10.1101/gad.1740808
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for HighWire
Loading ...
Support Center