Format

Send to

Choose Destination
See comment in PubMed Commons below
Langmuir. 2008 Dec 2;24(23):13266-9. doi: 10.1021/la8031573.

Real-time PCR in a plastic chip based on solid state FRET.

Author information

1
National Nanotechnology Laboratory of CNR-INFM, IIT Research Unit, Via per Arnesano 73100 Lecce, Italy.

Abstract

We show a novel solid state optical detection platform, integrated in a plastic biochip, based on colloidal nanocrystal FRET donors. The approach exploits a "smart" polymeric layer with both optical and biorecognition properties that allows real-time monitoring of biomolecular interactions and quantitative analyses of real-time PCR. The proposed strategy, demonstrated here for DNA detection, may open interesting perspectives for a wide range of applications, such as for proteomic studies.

PMID:
18980361
DOI:
10.1021/la8031573
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for American Chemical Society
    Loading ...
    Support Center