Vascular wall flow-induced forces in a progressively enlarged aneurysm model

Comput Methods Biomech Biomed Engin. 2008 Dec;11(6):615-26. doi: 10.1080/10255840802214999.

Abstract

The current study is focused on the numerical investigation of the flow field induced by the unsteady flow in the vicinity of an abdominal aortic aneurysm model. The computational fluid dynamics code used is based on the finite volume method, and it has already been used in various bioflow studies. For modelling the rheological behaviour of blood, the Quemada non-Newtonian model is employed, which is suitable for simulating the two-phase character of blood namely a suspension of blood cells in plasma. For examining its non-Newtonian effects a comparison with a corresponding Newtonian flow is carried out. Furthermore, the investigation is focused on the distribution of the flow-induced forces on the interior wall of the aneurysm and in order to study the development of the distribution with the gradual enlargement of the aneurysm, three different degrees of aneurysm-growth have been assumed. Finally and for examining the effect of the distribution on the aneurysm growth, a comparison is made between the pressure and wall shear-stress distributions at the wall for each growth-degree.

MeSH terms

  • Aneurysm / physiopathology*
  • Animals
  • Arteries / physiopathology*
  • Blood Flow Velocity*
  • Blood Pressure*
  • Computer Simulation
  • Elastic Modulus
  • Humans
  • Models, Cardiovascular*
  • Pulsatile Flow
  • Shear Strength
  • Stress, Mechanical