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J Vis Exp. 2007;(3):175. doi: 10.3791/175. Epub 2007 Apr 28.

Christopher Hughes: an in vitro model for the study of angiogenesis (interview).

Author information

1
Department of Molecular Biology and Biochemistry, University of California, Irvine, USA.

Abstract

Christopher C.W. Hughes describes the utility of his culture system for studying angiogenesis in vitro. He explains the importance of fibroblasts that secrete a critical, yet unidentified, soluble factor that allow endothelial cells to form vessels in culture that branch, form proper lumens, and undergo anastamosis.

PMID:
18978990
PMCID:
PMC2535841
DOI:
10.3791/175
[Indexed for MEDLINE]
Free PMC Article

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