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Diabetes Res Clin Pract. 2008 Dec 15;82 Suppl 2:S127-34. doi: 10.1016/j.diabres.2008.09.023. Epub 2008 Oct 31.

Fatty acid binding proteins in adipose tissue: a promising link between metabolic syndrome and atherosclerosis?

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1
Diabetes Centre, Institute for Clinical and Experimental Medicine, Vídenská 1958/9, 14021 Prague, Czech Republic.

Abstract

Adipocyte/macrophage fatty acid binding protein (A-FABP) has been shown to be closely associated with metabolic syndrome, obesity and development of atherosclerosis. Moreover, A-FABP has been recently suggested as a potential therapeutic target of these abnormalities in animal models. The present review aims to summarize current knowledge on A-FABP functions and regulations both in animal models and humans, since the role of A-FABP in human physiology and disease has not been presently clarified.

PMID:
18977052
DOI:
10.1016/j.diabres.2008.09.023
[Indexed for MEDLINE]
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