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J Indian Soc Pedod Prev Dent. 2008 Jan;26 Suppl 1:S5-10.

Endodontic treatment of primary teeth using combination of antibacterial drugs: an in vivo study.

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Department of Pedodontics and Preventive Dentistry, Bapuji Dental College and Hospital, Davangere 577 004, Karnataka, India.



The purpose of this study was to evaluate clinical and radiographic success of endodontic treatment of infected primary teeth using combination of ciprofloxacin, metronidazole, and minocycline.


The treatment was performed on selected 60 teeth, which were randomly divided into two groups, viz. Group A and B with 30 teeth in each group. In Group A, only the necrotic coronal pulp was removed, whereas in Group B both necrotic coronal as well as all accessible radicular pulp tissue was extirpated. The orifice of the canal was enlarged in both the groups and was termed as "Medication cavity." The medication cavity was half-filled with antibacterial mix, sealed with glass-ionomer cement and reinforced with composite resin. Resolution of clinical signs and symptoms was evaluated within a month after the treatment. At every subsequent visit, clinical and radiographic evaluation was done once in 6 months for a period of one year.


Both the groups showed considerable clinical and radiographic success, but Group B showed greater clinical and radiographic success than Group A.

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