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Res Vet Sci. 1991 Jul;51(1):24-8.

Antigenic diversity of Cowdria ruminantium isolates determined by cross-immunity.

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Department of Tropical Veterinary Medicine and Protozoology, Institute of Infectious Diseases and Immunology, Utrecht, The Netherlands.


Antigenic diversity in five stocks of the tick-borne rickettsia Cowdria ruminantium, the causal agent of heartwater disease of ruminants, was studied by cross-immunity trials in goats and sheep. Complete absence of cross-protection was found only between the Kümm and Kwanyanga stocks, and in all other combinations there were various degrees of cross-immunity. Immunological strain differences were more pronounced in goats than in sheep.

[Indexed for MEDLINE]

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