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Acta Haematol. 2008;120(2):100-3. doi: 10.1159/000165693. Epub 2008 Oct 29.

Rapid encephalopathy associated with anti-D immune globulin treatment for idiopathic thrombocytopenic purpura.

Author information

1
Department of Medicine, MetroWest Medical Center, Framingham, Mass., USA.

Abstract

Rho (D) immune globulin intravenous (IV RhIG, WinRho SDF) has been shown to be a safe treatment for idiopathic thrombocytopenic purpura. Common side effects of IV RhIG include mild hemolysis, febrile reaction and headache. Significant hemolysis with renal impairment is infrequently noted. A single case of irreversible encephalopathy following IV RhIG has been reported. We report a second case of encephalopathy following an infusion of IV RhIG for treatment of idiopathic thrombocytopenic purpura.

PMID:
18957844
DOI:
10.1159/000165693
[Indexed for MEDLINE]

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