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Mol Cell. 2008 Oct 24;32(2):162-4. doi: 10.1016/j.molcel.2008.10.008.

Death by splicing: tumor suppressor RBM5 freezes splice-site pairing.

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1
Department of Microbiology and Molecular Genetics, University of California, Irvine, Irvine, CA 92697-4025, USA.

Abstract

In a recent issue of Molecular Cell, Bonnal et al. (2008) demonstrate that the tumor suppressor gene RBM5 regulates alternative splicing of Fas pre-mRNA by interfering with splice-site pairing.

PMID:
18951082
DOI:
10.1016/j.molcel.2008.10.008
[Indexed for MEDLINE]
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