Relationships among blood pressure, triglycerides and verbal learning in African Americans

J Natl Med Assoc. 2008 Oct;100(10):1193-8. doi: 10.1016/s0027-9684(15)31474-7.

Abstract

Background: Individuals at greater risk for cardiovascular disease (CVD) display poorer cognitive functioning across various cognitive domains. This finding is particularly prevalent among older adults; however, few studies examine these relationships among younger adults or among African Americans.

Purpose: The objective was to examine the relationships among 2 cardiovascular risk factors, elevated blood pressure and elevated triglycerides, and verbal learning in a community-based sample of African Americans.

Methods: Measurements of blood pressure and triglycerides were obtained in 121 African-American adults and compared to performance on 3 domains of the California Verbal Learning Test-II (CVLT-II).

Results: Blood pressure was not related to CVLT-II performance. Triglyceride levels were inversely related to CVLT-II performance. Higher triglyceride levels were associated with poorer immediate, short delay and long delay recall.

Conclusions: Consistent with studies involving older participants, the current investigation shows that in a nonelderly sample of African Americans, triglyceride levels may be related to cognitive functioning. Because early detection and intervention of vascular-related cognitive impairment may have a salutary effect, future studies should include younger adults to highlight the impact of cardiovascular risk on cognition.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Aged
  • Black or African American*
  • Blood Pressure*
  • Female
  • Humans
  • Hypertension / epidemiology
  • Male
  • Middle Aged
  • Triglycerides / blood*
  • United States / epidemiology
  • Verbal Learning*

Substances

  • Triglycerides