Format

Send to

Choose Destination
Microvasc Res. 2009 Jan;77(1):4-7. doi: 10.1016/j.mvr.2008.09.004. Epub 2008 Sep 25.

Alteration of microvascular permeability in acute kidney injury.

Author information

1
Division of Nephrology, Department of Medicine, Indiana Center for Biological Microscopy, Indiana University School of Medicine, 950 West Walnut Street R-II, 202 Indianapolis, IN 46202, USA. tsutton2@iupui.edu

Abstract

Functional and structural abnormalities in the renal microvasculature are important processes contributing to the pathophysiology of ischemic acute kidney injury (AKI). Renewed interest in the complex interplay between tubular injury, inflammation and microvascular alterations has emerged in order to gain a better understanding of acute kidney injury syndromes. This review examines alterations of the renal microvasculature as they relate to ischemic and septic AKI with an emphasis on the mechanisms involved in altered microvascular permeability.

PMID:
18938184
PMCID:
PMC2680138
DOI:
10.1016/j.mvr.2008.09.004
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Elsevier Science Icon for PubMed Central
Loading ...
Support Center