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Chem Pharm Bull (Tokyo). 1991 Apr;39(4):1041-2.

A cytotoxic substance from Sangre de Grado.

Author information

1
Tokyo College of Pharmacy, Japan.

Abstract

Taspine has been isolated as a cytotoxic substance from Sangre de Grado, sap of Croton palanostigma (Euphorbiaceae), by bioassay guided fractionation. The cytotoxicity (IC50) of taspine was found to be 0.39 microgram/ml against KB cells and 0.17 microgram/ml against V-79 cells.

PMID:
1893488
DOI:
10.1248/cpb.39.1041
[Indexed for MEDLINE]

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