Format

Send to

Choose Destination
See comment in PubMed Commons below
Clin Cancer Res. 2008 Oct 15;14(20):6351-3. doi: 10.1158/1078-0432.CCR-08-1847.

Alphav integrins lead the way for colorectal metastases.

Author information

1
Department of Cancer Biology, University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA. jhmccarty@mdanderson.org

Abstract

In this issue of Clinical Cancer Research, Conti et al. identify a crucial cell adhesion and signaling axis that promotes the proliferation, survival, and drug-resistant properties of metastatic colorectal cancer cells in the liver. The components of this pathway may be effective targets for therapeutically treating established metastatic tumors in patients with colorectal adenocarcinomas.

PMID:
18927272
PMCID:
PMC2688736
DOI:
10.1158/1078-0432.CCR-08-1847
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire Icon for PubMed Central
    Loading ...
    Support Center