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Physiology (Bethesda). 2008 Oct;23:238-47. doi: 10.1152/physiol.00018.2008.

Nanoengineering ion channels for optical control.

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1
Institut de Bioenginyeria de Catalunya (IBEC), Institució Catalana de Recerca i Estudis Avançats (ICREA), and CIBER-BBN, Parc Científic de Barcelona, Barcelona, Spain.

Abstract

Chemical modification with photoisomerizable tethered ligands endows proteins with sensitivity to light. These optically actuated proteins are revolutionizing research in biology by making it possible to manipulate biological processes noninvasively and with unprecedented spatiotemporal resolution.

PMID:
18927200
DOI:
10.1152/physiol.00018.2008
[Indexed for MEDLINE]
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