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Graefes Arch Clin Exp Ophthalmol. 2009 Feb;247(2):267-72. doi: 10.1007/s00417-008-0960-y. Epub 2008 Oct 17.

Diabetic retinopathy and health-related quality of life.

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1
University of Cologne, Cologne, Germany.

Abstract

OBJECTIVE:

To describe the impact of co-morbidities, visual acuity, diabetic retinopathy (DR) grade, and macular edema (ME) on the health-related quality of life (HRQOL) among patients with diabetic retinopathy.

METHODS:

Analysis of data of 207 patients with diabetic retinopathy from Germany in 2003. HRQOL assessment was done using the generic (SF-12) questionnaire. It was hypothesized that exogenous variables (co-morbidities, visual acuity impairment, DR, and ME) would have an impact on HRQOL. Using a structural equation modelling procedure, the effects of exogenous variables on endogenous variables physical component summaries (PSC) and mental component summaries (MCS) reflecting HRQOL were tested.

RESULTS:

The number of co-morbidities had a negative effect on visual acuity (b = -0.26, standardized) and a similar negative effect on PCS (b = -0.27). DR grade had a negative effect on visual acuity (b = -0.19) and a positive effect on the variable ME (b = 0.44). ME displayed a negative effect on visual acuity (b = -0.58) and also on MCS (b = -0.29). Visual acuity had a positive effect (b = 0.48) on PCS.

CONCLUSIONS:

Presence of DR and ME, visual acuity impairment and patient co-morbidities lead to significant impairment of both the physical and mental components of HRQOL.

PMID:
18925408
DOI:
10.1007/s00417-008-0960-y
[Indexed for MEDLINE]

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