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Parasitol Res. 2009 Jan;104(2):341-5. doi: 10.1007/s00436-008-1198-7. Epub 2008 Oct 16.

Association of Blastocystis subtype 3 and 1 with patients from an Oregon community presenting with chronic gastrointestinal illness.

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  • 1Clinical Investigation Facility, David Grant USAF Medical Center, 101 Bodin Circle, Travis AFB, Fairfield, CA 94535, USA.

Erratum in

  • Parasitol Res. 2009 Jan;104(2):491. Boroom, Kenneth [corrected to Boorom, Kenneth].


Chronic gastrointestinal illness of unknown etiology is a significant problem in the United States. Using a real-time LightCycler PCR assay we detected Blastocystis in nine patients from a metropolitan area of Corvallis, Oregon who presented with diarrhea, abdominal pain, fatigue, joint pain, skin rash and psychiatric co-morbidity. Phylogenetic analysis identified six infections with Blastocystis sp. subtype 3, and one with subtype 1, using the standard Stensvold nomenclature. Most patients with subtype 3 had previously tested negative with conventional parasitological diagnostics, had been symptomatic for over 4 years, and reported antibiotic failure.

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