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Mol Cell. 2008 Sep 26;31(6):777-81. doi: 10.1016/j.molcel.2008.09.001.

Phosphoproteomics: unraveling the signaling web.

Author information

1
Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Abstract

In recent years, phosphoproteomic technologies have increased our understanding of cellular signaling networks. Here, we frame recent phosphoproteomics-based advances in the context of the DNA damage response and ErbB receptor family signaling and offer a perspective on how the molecular insights arising from the integration of such proteomic approaches might be used for clinical applications.

PMID:
18922462
PMCID:
PMC2754874
DOI:
10.1016/j.molcel.2008.09.001
[Indexed for MEDLINE]
Free PMC Article

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