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Br J Clin Pharmacol. 1991 May;31(5):553-5.

A comparison of serum and saliva paracetamol concentrations.

Author information

1
Anaesthetic Unit, St Thomas' Hospital, London.

Abstract

The relationship between serum and saliva paracetamol concentrations was investigated in twenty healthy volunteers. The plasma and saliva drug concentrations showed a significant correlation (r = 0.67). However the agreement between the two methods of measurement was poor with limits of agreement of -15.3 mg l-1 to +15.9 mg l-1 with mean sample values of 19.2 and 19.5 mg l-1 for plasma and saliva, respectively.

PMID:
1888625
PMCID:
PMC1368476
[Indexed for MEDLINE]
Free PMC Article

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