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Protein Pept Lett. 2008;15(8):843-9.

Structural bioinformatics study of PNP from Listeria monocytogenes.

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Faculdade de Biociências, Pontifícia Universidade Catílica do Rio Grande do Sul, Porto Alegre - RS, Brazil.


This work describes for the first time a model of Purine Nucleoside Phosphorylase from Listeria monocytogenes (LmPNP). We modeled the complexes of LmPNP with ligands in order to determine the structural basis for specificity. Comparative analysis of the model of LmPNP allowed identification of structural features responsible for ligand affinities.

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