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J Glaucoma. 2008 Oct-Nov;17(7):552-7. doi: 10.1097/IJG.0b013e31816299d4.

High prevalence of anxiety and depression in patients with primary open-angle glaucoma.

Author information

1
Department of Ophthalmology, University of Yamanashi, Yamanashi, Japan. fmabuchi@yamanashi.ac.jp

Abstract

PURPOSE:

To assess anxiety and depression in patients with primary open-angle glaucoma (POAG).

DESIGN:

Multicenter prospective case-control study.

PARTICIPANTS:

Two hundred thirty patients with POAG and 230 sex-matched and age-matched reference subjects with no chronic ocular conditions except cataracts.

INTERVENTION:

Anxiety and depression were evaluated using Hospital Anxiety and Depression Scale (HADS) questionnaire, which consists of 2 subscales with ranges of 0 to 21, representing anxiety (HADS-A) and depression (HADS-D).

MAIN OUTCOME MEASURE:

The prevalence of POAG patients with anxiety (a score of more than 10 on the HADS-A) or depression (a score of more than 10 on the HADS-D) was compared with that in the reference subjects. The prevalence of patients with depression was compared between the POAG patients with and without current beta-blocker eye drops.

RESULTS:

The prevalence (13.0%) of POAG patients with anxiety was significantly higher (P=0.030) than in the reference subjects (7.0%). The prevalence (10.9%) of POAG patients with depression was significantly higher (P=0.026) than in the reference subjects (5.2%). Between the POAG patients with and without beta-blocker eye-drops, no significant difference (P=0.93) in the prevalence of depression was noted.

CONCLUSIONS:

POAG was related to anxiety and depression. No significant relationship between the use of beta-blocker eye-drops and depression was noted.

PMID:
18854732
DOI:
10.1097/IJG.0b013e31816299d4
[Indexed for MEDLINE]

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