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Nat Neurosci. 2008 Nov;11(11):1264-6. doi: 10.1038/nn.2205. Epub 2008 Oct 12.

Memory reconsolidation mediates the strengthening of memories by additional learning.

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1
School of Psychology, University of Birmingham, Edgbaston, Birmingham, UK. j.l.c.lee@bham.ac.uk

Abstract

Memories are dynamic, rather than static, in nature. The reactivation of a memory through re-exposure to salient training stimuli results in its destabilization, necessitating a restabilization process known as reconsolidation, a disruption of which leads to amnesia. I found that one normal function of hippocampal memory reconsolidation in rats is to modify the strength of a contextual-fear memory as a result of further learning.

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PMID:
18849987
DOI:
10.1038/nn.2205
[Indexed for MEDLINE]
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