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Gene. 2009 Feb 15;431(1-2):13-7. doi: 10.1016/j.gene.2008.09.008. Epub 2008 Sep 18.

Biophysical studies with parallel stranded oligoduplex.

Author information

1
Laboratory 332, School of Life Sciences, Jawaharlal Nehru University, New Delhi-110067, India. pbhattacharya@mail.jnu.ac.in

Abstract

The thermal denaturation profiles of parallel stranded oligoduplexes during UV-spectroscopy and fluorescence spectroscopy, for the first time, were shown to follow the similar patterns as were described for antiparallel stranded oligoduplexes. The B-form structure of these center-bubble-forming oligoduplexes was determined with circular dichroism. Thermodynamic properties were also discussed.

PMID:
18848977
DOI:
10.1016/j.gene.2008.09.008
[Indexed for MEDLINE]

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