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Nat Rev Neurosci. 2008 Nov;9(11):856-69. doi: 10.1038/nrn2478. Epub 2008 Oct 9.

Functional role of the supplementary and pre-supplementary motor areas.

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Institute of Cognitive Neuroscience and Institute of Neurology, University College London, Alexandra House, 17 Queen Square, London, WC1N 3AR, UK.


The supplementary motor complex consists of the supplementary motor area, the supplementary eye field and the pre-supplementary motor area. In recent years, these areas have come under increasing scrutiny from cognitive neuroscientists, motor physiologists and clinicians because they seem to be crucial for linking cognition to action. However, theories regarding their function vary widely. This Review brings together the data regarding the supplementary motor regions, highlighting outstanding issues and providing new perspectives for understanding their functions.

[Indexed for MEDLINE]

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