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ScientificWorldJournal. 2008 Sep 21;8:901-4. doi: 10.1100/tsw.2008.115.

The microRNA-200 family regulates epithelial to mesenchymal transition.

Author information

1
Hanson Institute and Division of Human Immunology, Institute of Medical and Veterinary Science, Adelaide, SA 5000, Australia. emily.paterson@imvs.sa.gov.au

Abstract

Epithelial-mesenchymal transition (EMT) is implicated in metastasis initiation and has recently been shown to be regulated by the miRNA-200 family and miR-205. Expression of these miRNAs was lost in invasive breast cancer cell lines displaying mesenchymal-like morphology suggesting these microRNAs may play a role in cancer metastasis.

PMID:
18836656
PMCID:
PMC5848679
DOI:
10.1100/tsw.2008.115
[Indexed for MEDLINE]
Free PMC Article

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