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Curr Opin Cell Biol. 1991 Apr;3(2):230-4.

Cellular aging and senescence.

Author information

1
Biology of Aging Program, National Institute of Aging, Bethesda, Maryland 20892.

Abstract

Differentiated eukaryotic cells have only a finite capacity for cell division. This limitation is thought to be a cellular manifestation of organismal aging, and a restraint to tumor progression. The molecular basis for cellular senescence is not known, but a molecular framework for understanding this phenomenon has recently been established.

PMID:
1883615
[Indexed for MEDLINE]

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