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J Int Med Res. 2008 Sep-Oct;36(5):867-74.

Chronic fatigue syndrome and the central nervous system.

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1
Department of General Medicine, Kanazawa Medical University, Ishikawa, Japan.

Abstract

An increasing amount of neuroimaging evidence supports the hypothesis that chronic fatigue syndrome patients have structural or functional abnormalities within the brain. Moreover, some neurotrophic factors, neurotransmitters and cytokines have also been evaluated in order to elucidate the mechanism of abnormal neuropsychic findings in chronic fatigue syndrome. In this review, we suggest that the focal point of chronic fatigue syndrome research should be transferred to the central nervous system.

PMID:
18831878
DOI:
10.1177/147323000803600501
[Indexed for MEDLINE]
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