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J Invasive Cardiol. 2008 Oct;20(10):E296-300.

Spontaneous hemopericardium in a patient with hemophilia B: a case report and review of the literature.

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  • 1University of Michigan Health System, Ann Arbor, MI 48109-5368, USA.


Spontaneous hemopericardium is extremely rare in patients with hemophilia and has never been reported in hemophilia B-factor IX deficiency. We report a patient with hemophilia B who presented with spontaneous hemopericardium and tamponade requiring emergent pericardiocentesis. As advances in therapies improve the longevity and quality of life of patients with hemophilia, it is likely that adult interventional cardiologists will increasingly encounter these patients in the cardiac catheterization laboratory. We review the clinical challenges raised by this group of patients undergoing cardiac procedures and present a stepwise approach to optimal management during the periprocedural period.

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