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Diabetes Metab. 2008 Nov;34(5):447-54. doi: 10.1016/j.diabet.2008.08.001. Epub 2008 Sep 30.

The metabolic syndrome, diabetes and lung dysfunction.

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Division of Metabolic Diseases, Department of Clinical Medicine, University of Padova, Padova, Italy.


Sleep-disordered breathing and sleep apnoea are conditions frequently associated with comorbidity, including obesity, diabetes, hypertension, insulin resistance (metabolic syndrome) and cardiovascular disease. The diabetic state (type 1 and type 2 diabetes) may be associated to diminished lung function and, in particular, decreased vital capacity, and the association between chronic obstructive pulmonary disease (COPD) and type 2 diabetes may be due to a shared inflammatory process. Also, the alteration in circulating endothelial progenitor cells found in respiratory disease, the metabolic syndrome and cardiovascular disease reflect a common condition of endothelial dysfunction.

[Indexed for MEDLINE]

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