Synthesis of bornylmethyl- and isobornylmethyl-Δ8-THC (8c and 8d)
(a) (1) Mg/THF; (2) (1R)-(+)-camphor (3), reflux, 8 h; (b) p-TsOH·H2O, CH2Cl2, 45 °C, 1 h; (c) H2, 10% Pd/C, EtOH, r.t., (d) BBr3, CH2Cl2, 0 °C to r.t., (e) p-TsOH·H2O, CHCl3, 65 °C, 6 h.