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Int J Hematol. 2008 Oct;88(3):278-282. doi: 10.1007/s12185-008-0146-8. Epub 2008 Sep 26.

Multicentric Castleman's disease presenting with multiple nodes in lungs: a case report and literature review.

Author information

1
Department of Hematology, Peking Union Medical College Hospital, 1 ShuaiFuYuan, WangFuJing, Beijing, China.
2
Department of Hematology, Peking Union Medical College Hospital, 1 ShuaiFuYuan, WangFuJing, Beijing, China. hanbing-li@sina.com.

Abstract

We report a rare multicentric Castleman's disease case whose lung manifestation is severe than any known report. This is a 64-year-old woman, she had repeated cough, fever and breathlessness for more than 1 year. CT imaging showed multiple small nodules in both the lungs at the first onset. Large nodes and masses in both the lungs evolved 1 year later. After three times of lung biopsies (one video-assisted thoracoscopic surgery and two CT-guided percutaneous transthoracic), she was finally diagnosed as multicentric Castleman's disease. She got surprising relief after combination chemotherapy in spite of her severe lung changes.

PMID:
18815726
DOI:
10.1007/s12185-008-0146-8
[Indexed for MEDLINE]

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