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Zhonghua Wei Chang Wai Ke Za Zhi. 2008 Sep;11(5):408-13.

[Safety and feasibility of laparoscopic surgery and open surgery in ulcerative colitis: a meta-analysis].

[Article in Chinese]

Author information

1
Department of Colorectal Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.

Abstract

OBJECTIVE:

To compare the safety and feasibility of laparoscopic surgery and open surgery in ulcerative colitis.

METHODS:

A search of published studies in English and Chinese between January 1992 and May 2008 was performed. Nine hundred and twenty-three patients from 16 studies were recruited which met the inclusion criteria. Meta-analysis was performed through fixed effect model or random effect model dependent on heterogeneity.

RESULTS:

Compared to open procedure, patients with ulcerative colitis undergone laparoscopic surgery were able to tolerate oral intake significantly earlier (P<0.01) with shorter hospital stay (P<0.01) and had lower total complication rate (P<0.01). But duration of laparoscopic surgery was significantly longer than that of open procedure(P=0.04). Laparoscopic procedure was no more superior to open procedure in recovery of bowel function, re-operation rate, intra-abdominal abscess, anastomotic leak, postoperative bowel obstruction, wound infection, blood loss and mortality. The conversion rate was 4.2% in this analysis.

CONCLUSION:

Laparoscopic surgery for ulcerative colitis is safe and feasible with better recovery in short-term as compared to the open procedure.

PMID:
18803038
[Indexed for MEDLINE]

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