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J Pediatr Hematol Oncol. 2008 Jul;30(7):543-5. doi: 10.1097/MPH.0b013e318161a9f9.

A 13-year-old girl with cold agglutinin syndrome caused by anti-i.

Author information

1
Department of Transfusion Medicine and Serology, Harbor UCLA Medical Center, Torrance, CA 90509-2910, USA. hmm_md@yahoo.com

Abstract

A 13-year-old girl with cold agglutinin syndrome caused by anti-i was serologically positive for Epstein-Barr virus. The anti-i had a high titer at 4 degrees C and high thermal amplitude (reacting up to 37 degrees C with both cord i RBCs and the patient's autologous RBCs). The patient's hemoglobin dropped to 48 g/L. The age of the patient, the severity of the hemolysis, and the antibody specificity were unusual features of cold agglutinin syndrome. Transfusions with adult (I) red blood cells were effective.

PMID:
18797203
DOI:
10.1097/MPH.0b013e318161a9f9
[Indexed for MEDLINE]

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