Format

Send to

Choose Destination
See comment in PubMed Commons below
Arch Surg. 2008 Sep;143(9):866-70; discussion 871-2. doi: 10.1001/archsurg.143.9.866.

Treatment strategies and outcomes for rectal villous adenoma from a single-center experience.

Author information

  • 1Oregon Health & Science University, Portland, OR 97239, USA.

Abstract

OBJECTIVES:

To analyze a 13-year, single-surgeon experience with villous adenoma of the rectum with respect to procedure, complications, recurrence, and cancer incidence.

DESIGN:

Retrospective review of patient and tumor characteristics, procedure, recurrence, and complications.

SETTING:

University hospital.

PATIENTS:

Patients who underwent excision of rectal villous adenoma.

MAIN OUTCOME MEASURES:

Complication, recurrence, and malignancy rates.

RESULTS:

Thirty-six patients underwent 30 transanal and 10 transabdominal excisions. Mean age was 66 years (range, 41-86 years) and mean follow-up was 25 months (range, 0.5-132 months). Mean tumor size was 3.0 cm (range, 0.5-11 cm) and the mean distance of the tumor from the anal verge was 4.9 cm (range, 0-10 cm). Preoperatively, 18 (45%) lesions harbored low-grade dysplasia while 17 (43%) had high-grade dysplasia. Postoperative pathology was discordant in 50% of patients, including 5 of 40 lesions (13%) that were recategorized as invasive cancer. Tumor size did not correlate with malignancy. The complication rate was significantly lower in transanal compared with transabdominal excisions (3.6% vs 50%, P = .005). There were 4 (12.5%) benign recurrences, all after transanal excisions.

CONCLUSIONS:

Complete excision is warranted for rectal villous adenomas, as biopsies were accurate only 50% of the time, and 1 in 8 patients had unsuspected cancer found after excision. Transanal excision with negative margins is associated with low recurrence and complication rates and is the preferred approach, even with large lesions.

PMID:
18794424
DOI:
10.1001/archsurg.143.9.866
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Silverchair Information Systems
    Loading ...
    Support Center