Format

Send to

Choose Destination
J Invest Dermatol. 2008 Oct;128(10):2354-6. doi: 10.1038/jid.2008.236.

Germline MC1R variants and BRAF mutant melanoma.

Author information

1
Oncogenomics Laboratory, Queensland Institute of Medical Research, Brisbane, Queensland, Australia.

Abstract

Recent studies have demonstrated that melanocortin-1 receptor (MC1R) variants increase the risk of melanomas harboring BRAF mutations. This finding provides insight into the relationship between host genotype and selection for somatic mutation type. Additional larger studies are required in diverse populations to further examine the interaction between MC1R and BRAF in different melanoma subtypes.

PMID:
18787543
DOI:
10.1038/jid.2008.236
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center